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Naringenin |
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Product Name |
Naringenin |
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Latin Name |
Naringenin |
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Molecular Formula |
C15H12O5 |
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Molecular Weight |
272.25 |
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CAS NO |
93602-28-9 |
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Appearance |
White-like powder |
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Product Content |
≥98% |
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Analytical Method |
HPLC |
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Product Origin |
Citrus paradisi
Macfadyen |
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Action and Uses |
Naringenin is a potent inhibitor of the
cytochrome p450 liver enzymes: CYP1A2, CYP3A3 and CYP3A4.
There is however, considerable inter-individual variability
in the effects of grapefruit juice on drug metabolism, in
part due to 1) amount of naringenin formed by an individual,
2) amount of naringin present in a brand of grapefruit
juice, 3) dilution of grapefruit juice used, and 4) other
substances in grapefruit juice accounting for the
interaction.2 Researchers at the University of Western
Ontario in London discovered, while using various juices to
hide the taste of a test substance given to patients along
with their drugs as part of a cancer trial, that there was a
synergistic or more effective action of the drug to breast
cancer when it was given with Grapefruit Juice. From here,
researchers launched studies of other fruits to find out
why, and this is what they discovered. Human breast cancer
cells in test tubes that were estrogen-insensitive; that is,
the cells did not need estrogen to cock and prime them into
maligency, respond well to a flavonoid found in grape juice,
naringenin. Naringenin proved almost 8 times more potent at
halting breast cancer cells's growth than another flavonoid,
genestein from soy beans. You can now get the extract of the
grape in capsule form. Ask for Resveratrol at your favorite
health food store. |
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Analysis |
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Product content |
Naringenin≥98% |
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Sieve analysis |
100% pass 80 mesh |
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Loss on Drying |
≤1.0% |
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Residue on Ignition |
≤1.0% |
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Heavy Metal |
<20ppm |
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As |
<2ppm |
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Residual Solvents |
Eur.Pharm.2000 |
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Microbiology |
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Total Plate Count |
<1000cfu/g |
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Yeast & Mold |
<100cfu/g |
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E.Coli |
Negative |
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Salmonella |
Negative |
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Conclusion |
Conform with specification |
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Storage |
Store in sealed containers at cool & dry
place. Protect from light, moisture and pest infestation
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Shelf life |
2 year when properly stored |
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